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Oxidized Cholesterol in the Diet Accelerates the Development of  Atherosclerosis in LDL Receptor– and Apolipoprotein E–Deficient Mice -  Arteriosclerosis, Thrombosis, and Vascular Biology

The 4-Minute Rule for Oxidized Fatty Acids Promote Atherosclerosis Only in the

The oxycholesterol group revealed higher deposition of cholesterol in the lining of their arteries and a propensity to develop larger deposits of cholesterol. These fatty deposits, called atherosclerotic plaques, increase the risk for cardiovascular disease and stroke. Most significantly, according to Chen, oxycholesterol had unfavorable results on "artery function." Oxycholesterol decreased the flexibility of arteries, hindering their ability to expand and carry more blood. That growth can allow more blood to stream through arteries that are partly blocked by plaques, potentially reducing the risk that an embolisms will form and trigger a cardiovascular disease or stroke. But a healthy diet abundant in antioxidants can counter these effects, Chen said, noting that these compounds might block the oxidation process that forms oxycholesterol.

Healthy alternatives to fast-food, which also boosts oxycholesterol, consist of entire grains, fresh vegetables and fruits, seeds, and nuts. Scientists do not understand whether the popular anti-cholesterol drugs called statins lower oxycholesterol, Chen said. Hong Kong Grant Research study Council provided financing for this research study. An advisory body of the Hong Kong Unique Administration Area of the People's Republic of China, the Council is responsible for funding government-sponsored scholastic research study jobs.

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Your arteries are blood vessels that carry oxygen and nutrients from your heart to the rest of your body. In order for this essential process to occur, your arteries need to be versatile, strong, elastic and clear of any deposits. Nevertheless, over time deposits of fatty substances, cholesterol, cellular waste items, calcium and other substances can construct up in your arteries. These plaques can seriously limit blood circulation and, a lot more seriously, they can trigger your arteries to rupture, resulting in embolism.  Did you see this?  can then block your blood flow totally, resulting in cardiac arrest and stroke. In fact, a build-up of plaques in your arteries, understood as atherosclerosis, is the primary underlying cause of heart disease.